Good luck silkman ...------------------------------------------
Macron: AstraZeneca Vaccine Seems ‘Quasi-Ineffective’ On Older Peoplehttps://www.politico.eu/article/coronavirus-vaccine-europe-astrazeneca-macron-quasi-ineffective-older-pe/amp/PARIS — French President Emmanual Macron said Friday the AstraZeneca coronavirus vaccine appeared to be “quasi-ineffective” on people older than 65 — just hours before the EU’s drugs regulator approved it for use on all adults.
“The real problem on AstraZeneca is that it doesn’t work the way we were expecting it to,” Macron told a group of reporters, including POLITICO, in Paris. “We’re waiting for the EMA [European Medicines Agency] results, but today everything points to thinking it is quasi-ineffective on people older than 65, some say those 60 years or older.”
Later in the day, the EMA gave the vaccine the green light. It said: “There are not yet enough results in older participants (over 55 years old) to provide a figure for how well the vaccine will work in this group. However, protection is expected, given that an immune response is seen in this age group and based on experience with other vaccines; as there is reliable information on safety in this population, EMA’s scientific experts considered that the vaccine can be used in older adults.”
https://www.ema.europa.eu/en/news/ema-recommends-covid-19-vaccine-astrazeneca-authorisation-eu ... Macron said problems with the AstraZeneca jab will complicate the vaccination strategy in the EU, given that it is largely based on prioritizing vaccinating the senior population and healthcare workers. He said another unforeseen twist was that the vaccines that are more complicated to produce and store — those based on the mRNA technology that had never been used before to produce a vaccine — are the ones that appear to perform best.
... “When I listen to the scientists who say we accelerate the mutations with only one injection because the virus adapts… we are lying to people when we tell them they’ve been vaccinated by getting one injection of a vaccine that consists of two injections,” Macron added.
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Johnson & Johnson Covid-19 Vaccine is 66% Effective in Global Trial, But 85% Effective Against Severe Disease, Company Sayshttps://amp.cnn.com/cnn/2021/01/29/health/johnson-coronavirus-vaccine-results/index.htmlJohnson & Johnson's Covid-19 single-shot vaccine was shown to be 66% effective in preventing moderate and severe disease in a global Phase 3 trial, but 85% effective against severe disease, the company announced Friday.
The vaccine was 72% effective against moderate and severe disease in the US, the company said.
It's a striking difference from vaccines from Pfizer/BioNTech and Moderna, and it may give pause to people uncertain about which vaccine to get or when they can get one. The vaccines already on the market in the US are about 95% effective overall against symptomatic Covid-19, with perhaps even higher efficacy against severe cases.
The vaccine's efficacy against moderate and severe disease ranged from one country to another: 72% in the US, 66% in Latin America and 57% in South Africa. This was measured starting one month after the shot.
In South Africa, 95% of cases in the trial were due to a variant known as B.1.351, which is known to be more contagious and carries mutations that may make the virus less susceptible to the antibody immune response -- including antibodies prompted by vaccination.
https://www.jnj.com/johnson-johnson-announces-single-shot-janssen-covid-19-vaccine-candidate-met-primary-endpoints-in-interim-analysis-of-its-phase-3-ensemble-trialBut for Dr. Mathai Mammen, the company's global head of research and development, the key result was how effective the vaccine was at preventing severe disease -- regardless of variant or age group.
"Across all geographies, across all variants, we see 85% protection" against severe disease, he said. That trend increased over time, with no severe cases in the vaccinated group after day 49, according to the company.
From one month after the shot, all hospitalizations and deaths occurred in the placebo group.
The results are based on an analysis of more than 44,000 participants in eight countries, with 468 total cases of Covid-19 split between those receiving the vaccine or placebo. The results have not been published in a peer-reviewed journal, but the company said it plans to do so "in the coming weeks."
Side effects appear to be lower with this vaccine than the already approved ones, too.
Meanwhile, Novavax, a Gaithersburg, Maryland-based biotechnology firm, showed its COVID-19 candidate vaccine to be safe and roughly 90% effective against the virus
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CDC director Walensky: Community Spread of South African Variant Is Herehttps://www.cdc.gov/media/releases/2021/s0128-sc-detects-COVID-variant.html Rochelle Walensky, director of the Centers for Disease Control and Prevention, said that community spread of the highly contagious South African variant of the coronavirus is likely already occurring in the United States.
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‘People Are Scared’: COVID-19 Outbreak Rattles Crew of the Warship Chafeehttps://www.navytimes.com/news/your-navy/2021/01/29/people-are-scared-covid-19-outbreak-rattles-crew-of-the-warship-chafee/The
U.S. Chafee pulled into San Diego from Hawaii for training last Saturday and has been grappling with a COVID-19 outbreak that sailors onboard and internal documents obtained by Navy Times suggest is decimating the crew.
U.S. 3rd Fleet officials confirmed Wednesday that some
Chafee personnel had tested positive for the coronavirus, but declined to say how many cases had emerged among the guided-missile destroyer’s crew, citing Pentagon policy for not specifying such numbers.
“The ship remains able to meet its mission,” Cmdr. Sean Robertson said in an email Wednesday. “No Chafee sailors have been hospitalized and all positives are in isolation.”
But two petty officers aboard the ship tell Navy Times that dozens of sailors have been removed in recent days after either testing positive or coming in close contact with those who have.
A page from the ship’s “ROM Personnel Tracker” document obtained by Navy Times Wednesday shows 41 sailors listed as having either tested positive or been in close contact with infected shipmates out of a crew of about 350.
Geoff Ziezulewicz and David B. Larter
ROM is mil-speak for “Restriction of Movement,” the term for when service members quarantine for COVID-related reasons.
Eleven of those listed sailors are culinary specialists.One petty officer who asked to remain anonymous for fear of retribution said in a message to
Navy Times that several of the ship’s cooks tested positive for COVID-19 while the ship was transiting from Hawaii to San Diego, and that the galley has been closed for roughly a week as a result.
“Before pulling into San Diego we had seven people in quarantine and three tested positive, all the cooks that come into contact with the whole crew,” the petty officer said.
Another petty officer who also requested anonymity for fear of retribution said COVID cases have since spread to the information technology division, weapons department and engineering.
“No one is giving us information,” the petty officer added.
The sailors also questioned why the entire ship wasn’t getting tested for COVID.
“After they canceled the all-hands testing, we knew they didn’t want to deal with it,” the petty officer said.
One petty officer reported a shortage of N95 masks onboard, as well.
“Today, one of my junior sailors asked me what the difference is between the Navy and prison,” the petty officer said. “I didn’t have an answer for him. I was confused because this is not normal.”... “This is actually a very scary thing,” one petty officer said in a message Wednesday night. “They just quarantined five more people while I was telling you this.”
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Diamond Princess déjà vu all over again