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Author Topic: Lessons from COVID-19  (Read 55352 times)

SteveMDFP

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Re: Lessons from COVID-19
« Reply #400 on: December 10, 2021, 03:02:29 PM »
Imagine my surprise when watching this which seriously calls into question the very existence of virus's, one speaker from the point of view of what so called isolates actually are and another a food scientist used to studying actual contaminents in infinitesmal quantities who has been unable to acquire any quantified samples of cov19.

Which is how you know he's either a publicity-seeking fraud or a complete moron.  He expected to simply order viable Covid-19 from a laboratory supply company.  It's a dangerous pathogen.  Unless an institution has an accredited Biosafety 3-level lab or better, it's extremely unwise, unsafe, and illegal to even try to acquire such a pathogen.

This is virology.  Nobody sends dangerous "isolates" when all that's needed is the nucleic acid sequence.

NeilT

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Re: Lessons from COVID-19
« Reply #401 on: December 10, 2021, 05:41:17 PM »
Re: the numbers correlate closely to the numbers unvaccinated plus the 10% to 20% the vaccines cannot protect

And the evidence for this statement is ... ?

sidd

You can read a graph??

for the UK.

The UK has roughly 68m people.  Roughly 80% are vaccinated.  Only deaths and serious cases in hospital are relevant.  The UK is currently running circa 900 serious cases on a daily basis. The deaths you can see.

The vaccines work.  Numbers of "infections" Are irrelevant when they do not drive the number of deaths beyond levels we can cope with.  Witness the news out of ZA right now.

This is not conjecture.  But don't go looking for an analysis of these details, nobody really wants to talk about it.  Although England continues to say that actions will be taken when data shows that they are needed.  Current precautions are warranted until these data show otherwise.



Now here is a question which will really fry your mind.

If Omicron is truly a mild form of Covid from which almost nobody dies unless they are already highly at risk.  Then why would we want to stop it spreading?  Surely we would want to ringfence the vulnerable and let it "vaccinate" the population?

Or we can run around in circles screaming the sky is falling.

It is no wonder people have had enough, don't believe a word they are told and are on the streets rioting.
Being right too soon is socially unacceptable.

Robert A. Heinlein

NeilT

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Re: Lessons from COVID-19
« Reply #402 on: December 10, 2021, 05:55:46 PM »
O dear. Apparently, vaccination with these products ain't working so good ... Memoli makes a case for questioning broad mandates, but watch the whole thing if you have the time. The consensus is represented by the second speaker.

sidd

There is no point in watching the video when it claims the vaccines are not working.

Go back to the graphs I presented.  Start in spring 2020.  Cases/deaths.  Then winter 2020, cases, deaths.  Then autumn 2020, cases, deaths.

There is no need to watch a video of someone trying to disprove the validity of the vaccines.  The first round of the virus killed off the most vulnerable with relatively low cases.  The second round was really serious and the infections were not stopped by "hygiene" or "masks".  Only an environment suit or total isolation could absolutely stop the virus.

The third round has truly massive levels of cases, due to more transmissible virus in a more socially active community with less restrictions on protective materials.  Yet, in the third round, deaths are relatively low.  Compared to the number of daily cases they are tiny.

The vaccines work. They will continue working and all of this FUD about "maybe" they won't work is just that.  FUD.

The rest of the mess is political fear.

It is no wonder people are getting tired of the whole mess.  It is a virus, a global pandemic, it is going to kill people;  just as influenza does every single year.  At the millennium it is estimated that 65,000 people in the UK died as a result of that influenza epidemic.  I caught it too and it was horrible.  Masks?  NO. Lockdowns?  NO. Vaccinations?  Yes they were available and recommended for the vulnerable.
Being right too soon is socially unacceptable.

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sidd

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Re: Lessons from COVID-19
« Reply #403 on: December 11, 2021, 01:01:14 AM »
So in the statement " the numbers correlate closely to the numbers unvaccinated plus the 10% to 20% the vaccines cannot protect" the numbers refer only to deaths? or deaths + hospitalizations ?

The paper I cited by Singanayam et al. contradicts the claim that there is correlation between vaccination and COVID spread. It does not address deaths at all. But it does support the claim that vaccination does not affect spread.


sidd
« Last Edit: December 11, 2021, 01:07:23 AM by sidd »

blu_ice

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Re: Lessons from COVID-19
« Reply #404 on: December 11, 2021, 02:46:32 PM »
Many politicians in 2021 (post-vaccine) reacted to health system stresses and overloads. At least in Israel this recurred, no one wanted another lockdown but then it was forced on the decision makers by too many hospitalized.
Same here in Finland. But it’s interesting that we’re 21 months into the pandemic and no real effort to increase health care capacity has been made (spring 2020 emergency plans don’t count). The same politicians who are implementing vaccine passports and want to mass-test symptom-free schoolchildren, are somehow utterly unable to treat the other side of the problem which is insufficient health care capacity.

oren

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Re: Lessons from COVID-19
« Reply #405 on: December 11, 2021, 03:46:25 PM »
At least in Israel increasing hospital capacity is quite the challenge. Government budget is chronically stretched, and the main contraint is training new doctors and nurses. Health budget has been increased recently, but personnel is still hard to come by.
Despite the above, the third wave in Sep 2021 saw a much higher hospitalization burden before deciding on the lockdown, so in practice capacity was already increased thanks to better management and balancing between hospitals.

KiwiGriff

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Re: Lessons from COVID-19
« Reply #406 on: December 11, 2021, 09:26:17 PM »
Singanayam et al.

One paper is not conclusive evidence for such a complex question.
I would have thought relying on the conclusions of a single paper  would be something anyone who has followed the debate over AGW would be very careful about.
Animals can be driven crazy by placing too many in too small a pen. Homo sapiens is the only animal that voluntarily does this to himself.
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NeilT

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Re: Lessons from COVID-19
« Reply #407 on: December 11, 2021, 10:49:19 PM »
So in the statement " the numbers correlate closely to the numbers unvaccinated plus the 10% to 20% the vaccines cannot protect" the numbers refer only to deaths? or deaths + hospitalizations ?

Deaths, what else is important?

Those infected but not impacted are actually inoculated.  Those infected post vaccine but not hospitalised are shielded even more.

Vaccines prevent death more than infection. It is the only relevant metric.

Anything else is a smokescreen.
Being right too soon is socially unacceptable.

Robert A. Heinlein

Tor Bejnar

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Re: Lessons from COVID-19
« Reply #408 on: December 12, 2021, 02:07:26 AM »
I would amend:  Vaccines prevent death and hospitalization more than infection does. ...
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sidd

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Re: Lessons from COVID-19
« Reply #409 on: December 12, 2021, 08:32:55 AM »
Absolutely no one could have seen this coming:

"I think we will need the fourth dose,"

"https://thehill.com/policy/healthcare/585065-pfizer-ceo-says-fourth-vaccine-shot-may-eventually-be-needed

https://twitter.com/llyzs/status/1469250127798087687

Invest in Pfizer now!

sidd

aperson

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Re: Lessons from COVID-19
« Reply #410 on: December 12, 2021, 08:53:14 AM »
If you want to prevent infections wear n95 or better masks. If you want to prevent severe disease, follow an endless vaccination schedule. This is simply the reality of living with a respiratory virus that adapts faster than we do.
computer janitor by trade

sidd

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Re: Lessons from COVID-19
« Reply #411 on: December 13, 2021, 07:42:35 AM »
Another lesson from Illinois: unintended divisive natures

"scrapping his proposed legislation to make willfully unvaccinated people pay COVID-19 hospital bills out of pocket after he received violent threats that also targeted his family, staff and synagogue."

"Carroll announced that "due to the unintended divisive nature" of the bill, he has "decided not to pursue" it further."

"hope we can return to a more positive discourse"

"This is ridiculous,”

https://arstechnica.com/science/2021/12/amid-violent-threats-lawmaker-ditches-bill-to-make-unvaxxed-pay-hospital-bills/

sidd

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Re: Lessons from COVID-19
« Reply #412 on: January 12, 2022, 09:54:36 AM »
A view from China: wsws

"the ability to quickly identify close contacts of infected people. This is done using smartphone-based contact-tracing apps, cell phone location data and interviews with the patients themselves. After the first patient showed up in hospital and tested positive, his close contacts were rapidly identified and sent into quarantine, where they were regularly tested and their health was monitored."

"the central government requires each city to have the capacity to test its entire population within a short time frame. This means two days for cities with populations under 5 million, and within three to five days for cities with populations above 5 million. "

"The China CDC recently published an assessment of the consequences of embracing the “mitigation” strategy pursued by most countries, concluding that China’s health care system would be quickly overwhelmed by hundreds of thousands of daily COVID-19 cases, and more than 10,000 severe cases each day. “[E]mbrac[ing] certain ‘open-up’ strategies without reservation,” the China CDC warned, would “have a devastating impact on the medical system of China and cause a great disaster within the nation.” "

"Since the beginning of the pandemic, for each person temporarily quarantined in China (a country with four times the population of the United States), one American has died. "

https://www.wsws.org/en/articles/2021/12/13/chin-d13.html

sidd

NeilT

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Re: Lessons from COVID-19
« Reply #413 on: January 12, 2022, 10:58:03 AM »
It also helps when your medical staff, quarantine control staff and anyone dealing with positive people wear filtered masks which seal closely to the face, suits and gloves and have very little skin showing.

Just as if they were dealing with an infectious disease. :o

It will have a knock on effect though.  When the rest of the world opens up with populations who have largely been vaccinated and infected with less virulent strains of the virus, China will still be trying to hide from it.

What that will look like in the years to come I don't know, but it will be different.
Being right too soon is socially unacceptable.

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sidd

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Re: Lessons from COVID-19
« Reply #414 on: January 20, 2022, 03:21:49 AM »
Rasmussen poll:

-55% support fines for unvaccinated
-59% support house arrest for unvaccinated
-48% support prison for questioning vaccine efficacy on social media
-45% support internment camps for unvaccinated
-47% support surveillance of unvaccinated
-29% support the state taking children of unvaccinated

Which group does this refer to ?  democrats in the USA

https://www.rasmussenreports.com/public_content/politics/partner_surveys/jan_2022/covid_19_democratic_voters_support_harsh_measures_against_unvaccinated

sidd

oren

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Re: Lessons from COVID-19
« Reply #415 on: January 20, 2022, 09:52:53 AM »
I will humbly disbelieve the results of this poll, and note it was taken by the Heartland Institute which might be just a bit biased.

etienne

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Re: Lessons from COVID-19
« Reply #416 on: January 20, 2022, 01:43:26 PM »
I also can't believe that this pool has been done seriously. But it is clear that we have covidiots on both sides, vaccinated and unvaccinated.

SteveMDFP

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Re: Lessons from COVID-19
« Reply #417 on: January 20, 2022, 02:51:38 PM »
I will humbly disbelieve the results of this poll, and note it was taken by the Heartland Institute which might be just a bit biased.

Quite right.  In addition, the report notes that the methods included internet polling.  It's essentially impossible to acquire an unbiased sample from internet sites.

NeilT

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Re: Lessons from COVID-19
« Reply #418 on: January 20, 2022, 03:53:59 PM »
Out of 355 people polled, who identified as Democrats, they could find up to 195 of them who want stronger action on Covid.  Well I guess it depends where you look and as Steve has said, some places are very difficult to get true unbiased results.
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kassy

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Re: Lessons from COVID-19
« Reply #419 on: January 20, 2022, 04:01:03 PM »
I think we can stop on it being a crap poll. Also see orens post above.
Propaganda does not equal lessons.
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Tor Bejnar

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Re: Lessons from COVID-19
« Reply #420 on: January 20, 2022, 06:54:47 PM »
I agree, Kassy.  It is a little bit interesting, however, to see the views of people claiming to be Democrats who read right-wing propaganda sites.  These would include sure-fire Democrats who read the opposition and right-wingers pretending to be Democrats projecting the horrid things they think Democrats believe.  (One of the first group to 99 of the second?)

I still like the 2003 "What do you call a generic sweet non-alcoholic carbonated bottled beverage (and your zip code when growing up)?" internet poll.
Arctic ice is healthy for children and other living things because "we cannot negotiate with the melting point of ice"

sidd

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Re: Lessons from COVID-19
« Reply #421 on: January 20, 2022, 07:42:11 PM »
Re: Democrats who read right-wing propaganda sites

?

"Rasmussen Reports' survey questions are digitally recorded and fed to a calling program that determines question order, branching options, and other factors. Calls are placed to randomly-selected phone numbers through a process that ensures appropriate geographic representation."

"Rasmussen Reports uses an online survey tool to interview randomly selected participants from  a demographically diverse panel."

"the raw data is processed through a weighting program to ensure that the sample reflects the overall population in terms of age, race, gender, political party, and other factors. "

"the population targets are determined by census bureau data."

"For political surveys, census bureau data provides a starting point and a series of screening questions are used to determine likely voters. The questions involve voting history, interest in the current campaign, and likely voting intentions."

"Rasmussen Reports determines its partisan weighting targets through a dynamic weighting system that takes into account the state’s voting history, national trends, and recent polling in a particular state or geographic area."

https://www.rasmussenreports.com/public_content/about_us/methodology

sidd

kassy

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Re: Lessons from COVID-19
« Reply #422 on: January 20, 2022, 09:17:37 PM »
But the answers you give clicking on some multiple choice question on line are probably less nuanced then the things you would come up with if you actually had to think it through or debate it the whole way.

And ultimately over there the democrats and republicans have to work it out together.

In a way this survey would be better placed in the problems of social media thread or if Democrats who read right-wing propaganda sites is the issue then there is a thread for that in politics.
Þetta minnismerki er til vitnis um að við vitum hvað er að gerast og hvað þarf að gera. Aðeins þú veist hvort við gerðum eitthvað.

SteveMDFP

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Re: Lessons from COVID-19
« Reply #423 on: January 20, 2022, 09:32:30 PM »
Re: Democrats who read right-wing propaganda sites
...
"Rasmussen Reports uses an online survey tool to interview randomly selected participants from  a demographically diverse panel."

"the raw data is processed through a weighting program to ensure that the sample reflects the overall population in terms of age, race, gender, political party, and other factors. "  ...

Noted.  Still, these polling adjustments can't correct for the fact that online polling misses all people who spend no significant time online.  I imagine they place polling ads via Google ads, or the like.  Who ever sees these?  Certainly, nobody who spends their time on ASIF would ever see such a solicitation.  Likely, mostly social media users, especially Facebook.

Facebook users get fed items matching their biases and interests.  These are echo chambers.  Anti-Covid measure people are fed anti- propaganda, and pro-Covid measure people are fed pro- propaganda.  It's a prescription for a poll result describing the population as bitterly divided.

And I don't see how any demographic adjustments can correct for this bias.

sidd

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Re: Lessons from COVID-19
« Reply #424 on: January 21, 2022, 07:38:43 AM »
Mmm.

I run surveys thru several different companies for ... other ... purposes. What they seem to do is recruit a  bunch of different demo segments (Nielsen, Gallup, they all do this) in their panels. Then they use weighted samples out of all the people out of their panel for surveys. They weight the selection and the responses as described. Some of these guys have very large panels, i have run surveys across 27K people worldwide, that company had over a 100K panel to select from. Expensive.

I do not see any way that the panel would select for "Democrats who read right-wing propaganda sites" but i suppose if you use facebook or google analytics you could select for that. But i would like to see evidence that rasmussen did so for heartland.

Re: misses all people who spend no significant time online

Those are supposed to be covered by phone surveys, similar panels and selection

Actually i dont think Rasmussen is too far off the mark. My democratic friends are far, far more militant on COVID control than my republican or independent friends. Your mileage may vary.

Re:  don't see how any demographic adjustments can correct

All the major polling companies have detail on how they weight and correct. Not exactly rocket science, but they do get things wrong ... thus for example, Hillary beats Trump at 99 % ...

sidd
« Last Edit: January 21, 2022, 07:56:11 AM by sidd »

sidd

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Re: Lessons from COVID-19
« Reply #425 on: January 21, 2022, 07:50:16 AM »
Re: think it through or debate it the whole way.

Do let me know when you see a poll like that.

sidd

oren

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Re: Lessons from COVID-19
« Reply #426 on: January 21, 2022, 10:14:03 AM »
Poll results heavily depend on poll question wording. It's quite easy to manipulate and skew results with the choice of question. The article does not provide much in the way of raw data and questions, but the involvement of the Heartland institute, well known for lying in other fields, gives me confidence that these results are wrong or manipulated or presented in a biased way.

NeilT

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Re: Lessons from COVID-19
« Reply #427 on: January 21, 2022, 11:19:01 AM »
Being right too soon is socially unacceptable.

Robert A. Heinlein

KiwiGriff

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Re: Lessons from COVID-19
« Reply #428 on: January 21, 2022, 08:01:23 PM »
Hartland are well known to be right wing propaganda merchants.

Republican, Democrat, Other,  party affiliation. Conservative is political ideology yet no other data  follows.
The graphic  stops without a right hand border ?
There may be more information being suppressed/omitted because it does not coincide with the story they wish to present . 

Animals can be driven crazy by placing too many in too small a pen. Homo sapiens is the only animal that voluntarily does this to himself.
Notebooks of Lazarus Long.
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sidd

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Re: Lessons from COVID-19
« Reply #429 on: January 28, 2022, 09:04:36 AM »
Scocca at substack: USA unlimits COVID

"the United States is converging on an ever-more-clearly articulated answer to the coronavirus pandemic ... a nationwide Unlimited Covid policy."

"The result is the world's highest overall coronavirus death toll and the highest current daily number of deaths, as the nation of 330 million encourages the omicron variant to spread. Since the start of the pandemic, American life expectancy has declined by at least 1.8 years."

"the United States is focused on driving the number of closures, vaccination requirements, and mask orders down to zero. "

"Front-page stories in the New York Times, running with more than weekly frequency, warn the public of the perils of "Zero Covid" policy in China"

"With record numbers of Covid cases exhausting medical capacity in the United States, Americans are routinely turned away from their own country's emergency rooms, or crowded out of maternity units, or forced to delay surgeries. But the Unlimited Covid policy defines normalcy differently—as a matter of choice and of attitude. "

"The spectacle of leaders boasting about the country's economic performance, even while the death toll rises, recalls China's Great Leap Forward at the turn of the 1960s"

"By redefining its failure to control the coronavirus as a success, the United States has rewritten its social contract and reshaped the expectations of its people."

"Basic pandemic management—the Times disapprovingly described the Chinese regimen of "mass testing, stringent border controls, extensive contact tracing and snap lockdowns"—is considered something foreign and unrealistic. "

" China is a pandemic waiting to happen because the United States is wholeheartedly committed to being a pandemic. The American program, they say, will be the program for the entire world. "

https://indignity.substack.com/p/indignity-vol-2-no-7-the-american

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etienne

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Re: Lessons from COVID-19
« Reply #430 on: January 28, 2022, 01:45:12 PM »
On worldometer https://www.worldometers.info/coronavirus/#countries, the USA are in th 19th position regarding death per capita.

In front of them : eastern Europe, Brazil, Peru and urban states.

NeilT

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Re: Lessons from COVID-19
« Reply #431 on: January 28, 2022, 07:05:40 PM »
You have to be careful with what you read about Covid stats.

Yesterday I had to research some figures to shut up someone going on about how Omicron was killing so many people.

In the UK, if you test positive for covid, then die within 28 days, then you are a Covid death statistic.

We have seen active cases triple since Dec 2nd.  We have also seen deaths triple since Dec 2nd.

Great you say, that proves it doesn't it.

Not quite, we record one other stat. The number of people on ventilation machines.

Per infected person, the number of critical cases on ventilators is, today, nearly 6 times lower than it was on Dec 2nd.

So how do we get 3 times as many dead from covid if we have 6 times less critical?  Because if you are run down by a bus, struck by lightning, die in a car crash, fall into a river and drown, but are within that 28 day window, then you are a Covid death as far as the charts are concerned.

What we should have learned from this is that it is expensive in effort and money to give you the real numbers so they just give you the next best thing (for them).

The path in the UK is that the number of deaths are becoming close to being higher than the number of critical cases. At which point it becomes obvious to all.
Being right too soon is socially unacceptable.

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oren

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Re: Lessons from COVID-19
« Reply #432 on: January 28, 2022, 07:51:04 PM »
AFAIK people can die from Covid-19 without ever being on a ventilator.

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Re: Lessons from COVID-19
« Reply #433 on: January 29, 2022, 02:13:17 AM »
AFAIK people can die from Covid-19 without ever being on a ventilator.
Many do

NeilT

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Re: Lessons from COVID-19
« Reply #434 on: January 29, 2022, 10:07:43 AM »
There is a difference between dying "of" covid and dying "with" covid.

They are not the same thing. If you are a terminal cancer patient who catches covid in the last two weeks of your life, you did not die "of" covid.
Being right too soon is socially unacceptable.

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Richard Rathbone

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Re: Lessons from COVID-19
« Reply #435 on: January 29, 2022, 12:19:07 PM »
There is a difference between dying "of" covid and dying "with" covid.

They are not the same thing. If you are a terminal cancer patient who catches covid in the last two weeks of your life, you did not die "of" covid.

These aren't terminal patients. They are patients in hospital for something else, that catch COVID in hospital, and then die from the combination when they would have survived either on its own. This is looking like a much bigger problem with omicron, but its been a clear pattern with all COVID waves in the UK. The UK has very little slack before it has to compromise standards in its hospitals. Community transmission goes up, hospitals get under pressure, infection control breaks down, fatality rates go up.

The first three have happened for omicron to a record extent for the pandemic so far. It looks like the fatalities from compromised hospital care are going to be at record levels too.

NeilT

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Re: Lessons from COVID-19
« Reply #436 on: January 29, 2022, 01:00:10 PM »
How do you work that out?

Both hospital admissions and in hospital patients did not reach the peak of the second wave under Omicron.  Even with 3.6m active cases.

Neither did deaths reach the levels of the second wave.

The ratio of deaths to cases was significantly lower with Omicron.

The vaccines work.  The stats prove it.

The UK government has already admitted that the with and of figures are roughly 50% each. This is without a deep dive.

For most of this week covid recoveries have been significantly higher than new cases.  Critical cases continue to fall.

All with 3m active cases.
Being right too soon is socially unacceptable.

Robert A. Heinlein

morganism

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Re: Lessons from COVID-19
« Reply #437 on: July 29, 2024, 03:29:10 AM »
Stricter Covid mask rules could’ve saved hundreds of thousands of lives, new study finds

Restrictions in Northeastern states likely ‘saved many lives’ say researchers

The US could have avoided almost 250,000 Covid-19 deaths if every state had adopted stricter mask and vaccine requirements seen in the Northeast during the height of the pandemic, according to a new study.

Researchers say that the country, which saw more than 1.1 million Covid deaths, could have been spared an estimated 118,000 to 248,000 more lives.

The research from University of Virginia public policy and economics professor Christopher J Ruhm, published Friday in the Journal of the American Medical Association (JAMA) Health Forum, analyzed mortality data between 2020 and 2022, comparing it to a baseline of 2017 through 2019.

“These study findings do not support the views of those opposing COVID-19 restrictions who erroneously believe the restrictions did not work,” Ruhm writes. “To the contrary, the package of policies implemented by some states probably saved many lives.”

“If all states had imposed restrictions similar to those used in the 10 most restrictive states, excess deaths would have been an estimated 10% to 21% lower than the 1.18 million that actually occurred during the 2-year analysis period,” according to the study.

“Conversely, the estimates suggest counterfactual increases of 13% to 17% if all states had restrictions similar to those in the 10 least-restrictive states.”

During the outset of the pandemic, red and blue states alike implemented closures of public space, masking requirements, and other pandemic measures, but jurisdictions quickly diverged as the pandemic wore on and the science around the coronavirus was politicized.

It led to striking disparities. By 2021, for example, California schools required teachers to be vaccinated or tested regularly in the classroom, while Florida threatened to withhold pay from schools with mask mandates.

Ruhm’s data captures similar differences.

The excess death rate in Massachusetts, the state with the tightest Covid restrictions during the study period, was less than one-fifth that of Mississippi, the state with the loosest rules.

The lessons from the early years of the pandemic will surely be on lawmakers’ minds, as the US grapples with an outbreak of bird flu on poultry and cattle farms as well as a summer surge in Covid cases, with wastewater data showing spikes across the country.

https://www.independent.co.uk/news/world/americas/covid-mask-vaccine-rules-study-b2586693.html

....

US State Restrictions and Excess COVID-19 Pandemic Deaths

Question  How did state restrictions affect the number of excess COVID-19 pandemic deaths?

Findings  This cross-sectional analysis including all 50 US states plus the District of Columbia found that if all states had imposed COVID-19 restrictions similar to those used in the 10 most (least) restrictive states, excess deaths would have been an estimated 10% to 21% lower (13%-17% higher) than the 1.18 million that actually occurred during the 2-year period analyzed. Behavior changes were associated with 49% to 79% of this overall difference.

Meaning  These findings indicate that collectively, stringent COVID-19 restrictions were associated with substantial decreases in excess deaths during the pandemic.
Abstract

Importance  Despite considerable prior research, it remains unclear whether and by how much state COVID-19−related restrictions affected the number of pandemic deaths in the US.

Objective  To determine how state restrictions were associated with excess COVID-19 deaths over a 2-year analysis period.

Design, Setting, and Participants  This was a cross-sectional study using state-level mortality and population data from the US Centers for Disease Control and Prevention for 2020 to 2022 compared with baseline data for 2017 to 2019. Data included the total US population, with separate estimates for younger than 45 years, 45 to 64 years, 65 to 84 years, and 85 years or older used to construct age-standardized measures. Age-standardized excess mortality rates and ratios for July 2020 to June 2022 were calculated and compared with prepandemic baseline rates. Excess death rates and ratios were then regressed on single or multiple restrictions, while controlling for excess death rates or ratios, from March 2020 to June 2020. Estimated values of the dependent variables were calculated for packages of weak vs strong state restrictions. Behavioral changes were investigated as a potential mechanism for the overall effects. Data analyses were performed from October 1, 2023, to June 13, 2024.

Exposures  Age and cause of death.

Main Outcomes  Excess deaths, age-standardized excess death rates per 100 000, and excess death ratios.

Results  Mask requirements and vaccine mandates were negatively associated with excess deaths, prohibitions on vaccine or mask mandates were positively associated with death rates, and activity limitations were mostly not associated with death rates. If all states had imposed restrictions similar to those used in the 10 most restrictive states, excess deaths would have been an estimated 10% to 21% lower than the 1.18 million that actually occurred during the 2-year analysis period; conversely, the estimates suggest counterfactual increases of 13% to 17% if all states had restrictions similar to those in the 10 least-restrictive states. The estimated strong vs weak state restriction difference was 271 000 to 447 000 deaths, with behavior changes associated with 49% to 79% of the overall disparity.

Conclusions and Relevance  This cross-sectional study indicates that stringent COVID-19 restrictions, as a group, were associated with substantial decreases in pandemic mortality, with behavior changes plausibly serving as an important explanatory mechanism. These findings do not support the views that COVID-19 restrictions were ineffective. However, not all restrictions were equally effective; some, such as school closings, likely provided minimal benefit while imposing substantial cost.

https://jamanetwork.com/journals/jama-health-forum/fullarticle/2821581
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morganism

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Re: Lessons from COVID-19
« Reply #438 on: August 25, 2024, 10:21:04 PM »
The staggering death toll of scientific lies

Scientific fraud kills people. Should it be illegal?

(...)
I learned about the Poldermans case when I reached out to some scientific misconduct researchers, asking them a provocative question: Should scientific fraud be prosecuted?

Unfortunately, fraud and misconduct in the scientific community isn’t nearly as rare as one might like to believe. We also know that the consequences of being caught are frequently underwhelming. It can take years to get a bad paper retracted, even if the flaws are readily apparent. Sometimes, scientists alleged to have falsified their data file frivolous lawsuits against their peers who point it out, further silencing anyone who would speak out about bad data. And we know that this behavior can have high stakes, and can dramatically affect treatment options for patients.

In cases where research dishonesty is literally killing people, shouldn’t it be appropriate to resort to the criminal justice system?
(more)

https://www.vox.com/future-perfect/368350/scientific-research-fraud-crime-jail-time
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morganism

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Re: Lessons from COVID-19
« Reply #439 on: August 25, 2024, 10:31:52 PM »
Study: Air purifier use at daycare centres cut kids' sick days by a third

The results of the study at two Helsinki daycare centres are still preliminary but promising, a researcher says.

Use of air purifiers at two daycare centres in Helsinki led to a reduction in illnesses and absences among children and staff, according to preliminary findings of a new study led by E3 Pandemic Response.

Air purifiers of various sizes and types were placed in two of the city's daycare centres during cold and flu seasons.

The initial results from the first year of research are promising, according to researcher Enni Sanmark, from HUS Helsinki University Hospital.

"Children were clearly less sick in daycare centres where air purification devices were used — down by around 30 percent," Sanmark explained.

The air purifiers were changed at two daycare centres serving as a control in the experiment, in order to rule out the effect that possible epidemic fluctuations could have on the results. The study's next phase will continue until April.

"We will be able to analyse whether there were only decreases in flu-type illnesses or whether the use of air purification could also help reduce stomach ailments," Sanmark said.

On average, daycare centre-aged children suffer 10-13 infectious illnesses every year, with each illness lasting from one to three weeks, according to the research.

Meanwhile, kids between the ages of 1-3 come down with flu-like symptoms between five to eight times a year — and children also often suffer stomach bugs, on top of that. Kids are particularly prone to catching colds after returning to daycare after their summer break.

Those illnesses are often shared by the kids' parents and daycare staff, prompting absences from work.

Sanmark said that employers face costs of around 370 euros for one day of an employee's sick leave.

"It would be a big savings if we could get rid of 30 percent of sick days spread by children, as well as the illnesses that go home to parents," Sanmark said.

The research aims to help build an air purification scheme that could be used at other daycare centres — namely how to get the air cleaner at such facilities in ways that aren't too noisy, expensive or take up too much space.

The final results of the study are expected next spring.

"At the moment, we are cautiously positive. Daycares and schools [here] have not done this before, but of course results from around the world show that air purification can reduce pathogens in the air, so our results are in line with these findings. We're excited and will continue our research," Sanmark said.

Prompted by the Covid-19 crisis, the E3 Pandemic Response project is a private and public effort that aims to "harness modern science and technology to create effective countermeasures to prevent the spreading of novel infectious diseases".

https://yle.fi/a/74-20062381
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