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Sigmetnow

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Neuralink
« on: November 29, 2022, 03:23:25 PM »
—- Neuralink
Nov 30, 6 pm PT.
 
➡️ pic.twitter.com/I2J89Q7CYW 

14 seconds. Typing. Maybe someone using Neuralink???  “Please join us for show and tell”
 
11/24/22, 12:01 AM. https://twitter.com/neuralink/status/1595643786872225794

 —-
Quote
Ryan Tanaka 🤙✈️🌎.  @RyanTanaka3.
[host of @neurapod 
Neura Pod (Neuralink Updates) - YouTube
https://m.youtube.com/c/neurapod  ]
 
Neuralink is working on solving these brain/ spine problems:
 
- Memory loss
- Hearing loss
- Blindness
- Paralysis
- Depression
- Insomnia
- Extreme pain
- Seizures
- Anxiety
- Addiction
- Strokes
- Brain damage
11/24/22 https://twitter.com/ryantanaka3/status/1595667565803868160

—-
➡️ pic.twitter.com/JbZaoXBLxY
1 min. Neuralinked monkey playing pong with his mind. (While sipping on a banana smoothie.)
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Sigmetnow

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Re: Neuralink
« Reply #1 on: November 30, 2022, 03:20:36 AM »
Quote
Metro @MetroUK
The co-founder of @neuralink has revealed plans for an eye implant that could one day provide a cure for blindness 🤯
 
Here's what we know so far:
  —
Called the ‘Science Eye’, it plans to tackle to distinct types of blindess for which there is currently no cure: retinitis pigmentosa (RP) and dry age-related macular degeneration (AMD).
  —
As you’d expect from someone who worked with Elon Musk to build a brain-computer interface company, the Science Eye is suitably sci-fi...  pic.twitter.com/519gPXaoGD
  —
It will work by stimulating the optic nerve with an implanted, flexible ultradense microLED display panel inserted directly over the retina. The company will then employ gene therapy to act as a go-between and link the two.  pic.twitter.com/UT8dS2GWct
  —
Eventually, the Science Eye could work as a brain-computer interface itself and bestow cyborg-style benefits to wearers 🤯
This could include removing the need for glasses or even serving as a virtual reality device instead of a clunky headset 🤓
  —
@maxhodak_, the former Neuralink president, is behind the technology and says his startup Science Corp has already raised $160 million (£132 million) to commercialise the tech.
  —
Hodak’s company is going down a different route than Neuralink, which drills holes in a patient’s skull to insert electrodes into the brain. Instead, Science Corp wants to use photoreceptors to pass information through the optic nerve and into the brain.
  —
Would you ever consider getting a brain implant?
[poll results:  yes 54%, no 46%]
  —
And while the company says it will initially start work on animals, it hopes to get the implant into human patients in the not-too-distant future 👀

For the full story 👇
 
Cyborg eye implant could one day restore sight by linking to the brain | Metro News
https://metro.co.uk/2022/11/25/cyborg-eye-implant-could-one-day-restore-sight-by-linking-to-the-brain-17827214/
 
11/25/22 https://twitter.com/metrouk/status/1596118693351915521
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Sigmetnow

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Re: Neuralink
« Reply #2 on: November 30, 2022, 07:25:22 PM »
—- Update from @neuralink at 6pm PT
Quote
Neuralink
We’ll be doing a live Q&A during today’s event. If you have a question you’d like to ask, reply here.
11/30/22, 10:02 AM. https://twitter.com/neuralink/status/1597969445430865923
 
Neuralink Show and Tell, Fall 2022 - YouTube



Potential strong demand for Neuralink as a cure for tinnitus.
Quote
@elonmusk answered my question about Neuralink as a possible cure for tinnitus. My question is “once proven safe, will there be an age limit to receiving a Neuralink implant”?
I would be a willing recipient! 
11/30/22 https://twitter.com/jameswlaw1/status/1597982424839106561
Other replies also welcome such a cure.
⬇️ Twitpic below.

The Cost of a Neuralink Implant - YouTube
10 min. vid.   $3-5k including insurance.
 
People who say it cannot be done should not interrupt those who are doing it.

Sigmetnow

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Re: Neuralink
« Reply #3 on: December 01, 2022, 06:39:13 PM »
Yes, the monkeys are typing.  But it’s a game for them — they still can’t spell. 😅

Neurapod
SUPERCUT: Neuralink Show & Tell Event (23 Minutes)


Musk’s Neuralink Hopes to Implant Computer in Human Brain in Six Months
The startup awaits implant approval while already working on curing paralysis
November 30, 2022
Quote
Elon Musk’s Neuralink Corp. aims to start putting its coin-sized computing brain implant into human patients within six months, the company announced at an event at its Fremont, Calif. headquarters on Wednesday evening.

Neuralink has been refining the product, which consists of a tiny device and electrode-laced wires, along with a robot that carves out a piece of a person’s skull and implants it into the brain. Ongoing discussions with the US Food and Drug Administration have gone well enough for the company to set a target of its first human trials within the next six months, according to Musk.
https://www.bloomberg.com/news/articles/2022-12-01/musk-s-neuralink-hopes-for-human-trials-approval-within-six-months

Quote
“We are now confident that the Neuralink device is ready for humans, so timing is a function of working through the FDA approval process.”
11/30/22, 10:19 PM. https://twitter.com/elonmusk/status/1598154904635596802

Quote
"My prime motivation for Neuralink was the question: 'What do we do if there is a superintelligence that is much smarter than human beings? How do we, as a species, mitigate the risk or, in a benign scenario, go along for the ride?'"
11/30/22 https://twitter.com/elonmusk/status/1598155318319775746
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vox_mundi

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Re: Neuralink
« Reply #4 on: December 06, 2022, 08:49:32 PM »
Musk’s Neuralink Faces Federal Inquiry After Killing 1,500 Animals In Testing
https://www.theguardian.com/technology/2022/dec/05/neuralink-animal-testing-elon-musk-investigation

Elon Musk's brain-computer interface company Neuralink is under investigation by the US Department of Agriculture for possible animal welfare violations amid allegations from current and former employees that the company abused animals in slapdash research leading to "hack job" surgeries that led to needless pain and suffering of animals before they were euthanized, spurred by Musk's rushed timelines, according to documents reviewed by Reuters and sources familiar with the investigation and company operations.

The federal investigation, which has not been previously reported, was opened in recent months by the US Department of Agriculture’s inspector general at the request of a federal prosecutor, according to two sources with knowledge of the investigation. The inquiry, one of the sources said, focuses on violations of the Animal Welfare Act, which governs how researchers treat and test some animals.

The investigation has come at a time of growing employee dissent about Neuralink’s animal testing, including complaints that pressure from Musk to accelerate development has resulted in botched experiments, according to a Reuters review of dozens of Neuralink documents and interviews with more than 20 current and former employees. Such failed tests have had to be repeated, increasing the number of animals being tested and killed, the employees say. The company documents include previously unreported messages, audio recordings, emails, presentations and reports.

... In all, the company has killed about 1,500 animals, including more than 280 sheep, pigs and monkeys, following experiments since 2018, according to records reviewed by Reuters and sources with direct knowledge of the company’s animal-testing operations. The sources characterized that figure as a rough estimate because the company does not keep precise records on the number of animals tested and killed. Neuralink has also conducted research using rats and mice.

Current and former Neuralink employees say the number of animal deaths is higher than it needs to be for reasons related to Musk’s demands to speed research. Through company discussions and documents spanning several years, along with employee interviews, Reuters identified four experiments involving 86 pigs and two monkeys that were marred in recent years by human errors. The mistakes weakened the experiments’ research value and required the tests to be repeated, leading to more animals being killed, three of the current and former staffers said. The three people attributed the mistakes to a lack of preparation by a testing staff working in a "pressure-cooker environment".

Overall, employees blamed the avoidable accidents on Musk pushing researchers for faster progress with rushed timelines and deadlines.

One employee, in a message seen by Reuters, wrote an angry missive this year to colleagues about the need to overhaul how the company organizes animal surgeries to prevent “hack jobs”. The rushed schedule, the employee wrote, resulted in under-prepared and over-stressed staffers scrambling to meet deadlines and making last-minute changes before surgeries, raising risks to the animals.

This year, the chief executive sent staffers a news article about Swiss researchers who developed an electrical implant that helped a paralyzed man to walk again. “We could enable people to use their hands and walk again in daily life!” he wrote to staff at 6.37am Pacific time on 8 February. Ten minutes later, he followed up: “In general, we are simply not moving fast enough. It is driving me nuts!”

On several occasions over the years, Musk has told employees to imagine they had a bomb strapped to their heads in an effort to get them to move faster, according to three sources who repeatedly heard the comment. On one occasion a few years ago, Musk told employees he would trigger a “market failure” at Neuralink unless they made more progress, a comment perceived by some employees as a threat to shut down operations, according to a former staffer who heard his comment.

One former employee who asked management several years ago for more deliberate testing was told by a senior executive it wasn’t possible given Musk’s demands for speed, the employee said. Two people told Reuters they had left the company over concerns about animal research.

... The mistakes leading to unnecessary animal deaths included one instance in 2021 when 25 out of 60 pigs in a study had devices that were the wrong size implanted in their heads, an error that could have been avoided with more preparation, according to a person with knowledge of the situation and company documents and communications reviewed by Reuters.

The mistake raised alarm among Neuralink’s researchers. In May 2021, Viktor Kharazia, a scientist, wrote to colleagues that the mistake could be a “red flag” to FDA reviewers of the study, which the company planned to submit as part of its application to begin human trials. His colleagues agreed, and the experiment was repeated with 36 sheep, according to the person with knowledge of the situation. All the animals, both the pigs and the sheep, were killed after the procedures, the person said.

On another occasion, staff accidentally implanted Neuralink’s device on the wrong vertebra of two different pigs during two separate surgeries, according to two sources with knowledge of the matter and documents reviewed by Reuters.

The company veterinarian Sam Baker advised his colleagues to immediately kill one of the pigs to end her suffering.

“Based on low chance of full recovery … and her current poor psychological wellbeing, it was decided that euthanasia was the only appropriate course of action,”
Baker wrote colleagues about one of the pigs a day after the surgery, adding a broken heart emoji. 💔

Neuralink executives have said publicly that the company tests animals only when it has exhausted other research options, but documents and company messages suggest otherwise. During a 30 November presentation the company broadcast on YouTube, for example, Musk said surgeries were used at a later stage of the process to confirm that the device worked rather than to test early hypotheses. “We’re extremely careful,” he said, to make sure that testing is “confirmatory, not exploratory”, using animal testing as a last resort after trying other methods.

In October, a month before Musk’s comments, Autumn Sorrells, the head of animal care, ordered employees to scrub “exploration” from study titles retroactively and stop using it in the future.

Neuralink records reviewed by Reuters contained numerous references over several years to exploratory surgeries, and three people with knowledge of the company’s research strongly rejected the assertion that Neuralink avoids exploratory tests on animals. Company discussions reviewed by Reuters showed several employees expressing concerns about Sorrells’ request to change exploratory study descriptions, saying it would be inaccurate and misleading.

One noted that the request seemed designed to provide “better optics” for Neuralink.
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Sigmetnow

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Re: Neuralink
« Reply #5 on: December 07, 2022, 07:40:23 PM »
How long does it take to identify which vertebra is to be operated on, or which exact unit is to be implanted?  Such mistakes sound like a too-relaxed environment, exactly the kind that needs pressure to excel.  The recent Neuralink presentation showed a myriad of ways the company is manufacturing, testing and improving the units and the surgical robot without using animals at all.

From the same article:
Quote
The total number of animal deaths does not necessarily indicate that Neuralink is violating regulations or standard research practices. Many companies routinely use animals in experiments to advance human health care, and they face financial pressure to quickly bring products to market. The animals are typically killed when experiments are completed, often so they can be examined post-mortem for research purposes.

“Reuters could not determine the full scope of the federal investigation or whether it involved the same alleged problems with animal testing identified by employees in Reuters interviews.”

“Regulatory filings show that Neuralink has passed previous USDA inspections.”
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Sigmetnow

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Re: Neuralink
« Reply #6 on: April 01, 2023, 05:24:07 PM »
Quote
Neuralink @neuralink
Bath time! 🛁 Our accelerated lifetime tester ages our implants at 4x speed. Developing new ways of expediting long-duration testing at scale allows us to iterate faster, identify low probability failures, and reduce animal use #techtuesday
3/28/23 https://twitter.com/neuralink/status/1640857347575693316
 
➡️ pic.twitter.com/n25TV32hnz. 30 sec.
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Sigmetnow

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Re: Neuralink
« Reply #7 on: May 26, 2023, 03:04:27 AM »
Elon Musk's brain implant company Neuralink announces FDA approval of in-human clinical study
Quote
Neuralink, the neurotech startup co-founded by Elon Musk, announced Thursday it has received approval from the Food and Drug Administration to conduct its first in-human clinical study.

Neuralink is building a brain implant called the Link, which aims to help patients with severe paralysis control external technologies using only neural signals. This means patients with severe degenerative diseases like ALS could eventually regain their ability to communicate with loved ones by moving cursors and typing with their minds.

"This is the result of incredible work by the Neuralink team in close collaboration with the FDA and represents an important first step that will one day allow our technology to help many people," the company wrote in a tweet.

The extent of the approved trial is not known. Neuralink said in a tweet that patient recruitment for its clinical trial is not open yet.

Neuralink is part of the emerging brain-computer interface, or BCI, industry. A BCI is a system that deciphers brain signals and translates them into commands for external technologies. …

Scientists have been studying BCI technology for decades, and several companies have developed promising systems that they hope to bring to market. But receiving FDA approval for a commercial medical device is no small task — it requires companies to successfully conduct several extremely thorough rounds of testing and data safety collection.

No BCI company has managed to clinch the FDA's final seal of approval. But by receiving the go-ahead for a study with human patients, Neuralink is one step closer to market. …
https://www.msn.com/en-us/health/other/elon-musks-brain-implant-company-neuralink-announces-fda-approval-of-in-human-clinical-study/ar-AA1bHITJ
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Bruce Steele

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Re: Neuralink
« Reply #8 on: May 26, 2023, 06:15:52 AM »
Sigmetnow, Seems like a big step. FDA approval . Not a small thing and something that when we are looking back someday , a huge step. When humans made a first direct link with AI, as an implant.
Thanks for the news, Sigmetnow , even though somehow the idea of restoring communication with the severely disabled seems reasonable lord knows where DARPA will take this. Too much SCI - FI in my youth maybe.

Sigmetnow

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Re: Neuralink
« Reply #9 on: May 26, 2023, 07:44:55 PM »
Bruce, thanks for the encouraging words.  Many attack what they do not understand, but there are people with neurological disorders including chronic pain, emotional disorders and paralysis that can find no relief with today’s medical science and desperately await new solutions this may bring.

Quote
Brian Krassenstein @krassenstein

Yesterday it was announced that the Elon Musk-founded, brain-computer-interface company Neuralink got the FDA’s approval to launch their first clinical study.

I see a lot of people attacking this news for some reason.

4 Reasons Why I'm Excited:

1) Neuralink holds the potential to revolutionize the field of medicine by providing new treatments for neurological disorders.

2) Neuralink has the potential to restore lost functionality to the human body. For instance, it could enable direct communication between the brain and prosthetic limbs, allowing amputees to control artificial limbs with greater precision and dexterity. That's just one example.

3) Neural interfaces have the potential to enhance human cognitive abilities. The best solution to the fear of AI could be the enhancement of the Human brain with AI. 

4) Neuralink's development could significantly contribute to our understanding of the human brain. By studying the brain's neural activity through implanted devices, researchers can gain information into how the brain works, potentially leading to breakthroughs in neuroscience and mental health treatment.

Please stop attacking positive things just because they are connected with someone you may not like.

The world needs progress, and this is progress!
5/26/23 https://twitter.com/krassenstein/status/1662039920054087681
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nadir

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Re: Neuralink
« Reply #10 on: May 26, 2023, 11:16:38 PM »
Ignore these rascals (Krassenstein). They are benefited by Musk, clearly. From shills of the Dem Party to cheer leaders of Musk? Something smells rotten.

Others are noting that there’s no official FDA communication (yet)
https://twitter.com/panz2021/status/1662163113519751168?s=46&t=fgkWfKCeMHNTP58vSU0TeA

Sigmetnow

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Re: Neuralink
« Reply #11 on: May 27, 2023, 01:05:05 PM »
Quote
The FDA doesn’t typically confirm approvals for human clinical trials but offered a statement Friday. “The FDA acknowledges and understands that Neuralink has announced that its investigational device exemption … for its implant/R1 robot was approved by the FDA and that it may now begin conducting human clinical trials for its device,” an agency spokesperson said in a statement Friday.

Founded in 2016, Neuralink is a privately held firm with operations in Fremont, Calif., and a sprawling campus under construction outside of Austin. The company has more than 400 employees and has raised at least $363 million, according to data-provider PitchBook.

Neuralink has brought extraordinary resources — and investor attention — to a field known as brain-computer interface, where scientists and engineers are developing electronic implants that would decode brain activity and communicate it to computers. Such technology, which has been in the works for decades, has the potential to restore function to people with paralysis and debilitating conditions like amyotrophic lateral sclerosis.

Already, companies like Blackrock Neurotech and Synchron have implanted devices in people for clinical trials, and at least 42 people globally have had brain-computer implants. Such devices have enabled feats that once belonged to the realm of science fiction: a paralyzed man fist-bumping President Barack Obama with a robotic hand; a patient with ALS typing by thinking about keystrokes; a tetraplegic patient managing to walk with a slow but natural stride.

What is Neuralink’s brain chip technology?
The company has designed an electrode-laden computer chip to be sewn into the surface of the brain, and a robotic device to perform the surgery. Neuralink is pursuing a more invasive, high-bandwidth approach than some of its rivals, betting that its configuration will transfer data from brain to computer more rapidly than devices with fewer electrodes or that sit outside the brain’s surface.

[T]he company has also given lengthy, highly technical presentations on its technology, discussing such topics as how it will mitigate the risk of brain tissue scarring and a diminishing electronic signal from the implant.

It is unclear when clinical trials might begin. A patient registry on Neuralink’s website indicates that only patients with certain conditions — including paralysis, blindness, deafness or the inability to speak — are eligible to participate.
https://www.washingtonpost.com/business/2023/05/25/elon-musk-neuralink-fda-approval/
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