the pandemic was politicized and weaponized right out of the gates so i don't know why it's moved here now. the main take-away is how corrupted the entire scientific undertaking has become, "the science" is destroying science. the british medical journal was highlighting this throughout the pandemic. why aren't people still following science and posting studies on the other thread anymore? when i do they just get ignored like it's early 2022 as though "the science" is still valid.
Risk of Coronavirus Disease 2019 (COVID-19) among Those Up-to-Date and Not Up-to-Date on COVID-19 Vaccination
https://www.medrxiv.org/content/10.1101/2023.06.09.23290893v1ABSTRACT
Background The CDC recently defined being “up-to-date” on COVID-19 vaccination as having received at least one dose of a COVID-19 bivalent vaccine. The purpose of this study was to compare the risk of COVID-19 among those “up-to-date” and “not up-to-date” on COVID-19 vaccination.
Methods Employees of Cleveland Clinic in employment when the COVID-19 bivalent vaccine first became available, and still employed when the XBB lineages became dominant, were included.
Cumulative incidence of COVID-19 since the XBB lineages became dominant was compared across the “up-to-date” and “not up-to-date” states, by treating COVID-19 bivalent vaccination as a time-dependent covariate whose value changed on receipt of the vaccine. Risk of COVID-19 by vaccination status was also compared using multivariable Cox proportional hazards regression adjusting for propensity to get tested for COVID-19, age, sex, and phase of most recent prior SARS-CoV-2 infection.
Results COVID-19 occurred in 1475 (3%) of 48 344 employees during the 100-day study period. The cumulative incidence of COVID-19 was lower in the “not up-to-date” than in the “up-to-date” state. On multivariable analysis, not being “up-to-date” with COVID-19 vaccination was associated with lower risk of COVID-19 (HR, 0.77; 95% C.I., 0.69-0.86; P-value, <0.001). Results were very similar when those 65 years and older were only considered “up-to-date” after receiving 2 doses of the bivalent vaccine.
Conclusions Since the XBB lineages became dominant, adults “not up-to-date” by the CDC definition have a lower risk of COVID-19 than those “up-to-date” on COVID-19 vaccination, bringing into question the value of this risk classification definition.
Summary Among 48 344 working-aged Cleveland Clinic employees, those not “up-to-date” on COVID-19 vaccination had a lower risk of COVID-19 than those “up-to-date”. The current CDC definition provides a meaningless classification of risk of COVID-19 in the adult population.
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IgG4 Antibodies Induced by Repeated Vaccination May Generate Immune Tolerance to the SARS-CoV-2 Spike Protein
https://www.mdpi.com/2076-393X/11/5/991"Increased IgG4 synthesis due to repeated mRNA vaccination with high antigen concentrations may also cause autoimmune diseases, and promote cancer growth and autoimmune myocarditis in susceptible individuals."
"Finally, these negative outcomes are not expected to affect all people who have received these mRNA vaccines. Individuals with genetic susceptibility, immune deficiencies, and comorbidities are probably the most likely to be affected. However, this gives rise to a disturbing paradox—if people who are the most affected by the COVID-19 disease (the elderly, diabetics, hypertensive, and immunocompromised people like those with HIV) are also more susceptible to suffering the negative effects of repeated mRNA vaccination, is it then justified to booster them? As Omicron subvariants have been demonstrated to be less pathogenic [133,134,135,136,137], and mRNA vaccines do not protect against re-infection [14,138], clinicians should be aware of the possible detrimental effects on the immune system by administering boosters."
we learned that scientific understanding around respiratory viruses, coronavirus vaccines and mrna vaccines prior to the pandemic is still valid, despite "the science" desperately trying to pretend otherwise. we learned how people will behave towards each other when authorities authorize demonizing a group deemed sub-human and worthy of erasure, this validates old psychological studies. we also learned a great deal about elite plans for our techno-utopian future.
in the end we learned how irrational and easily manipulated people are and when confronted with contradictory evidence they'll continue to believe what they've been told to believe, hear only what they want, and see only that which confirms their bias.
this message should be censored - delete, delete, delete.