My answer #2. now assuming that John insist on not being 'locked in':
Start project to build "Cause -> Consequence" Network (or graph if you like), CCN.
In this network we have a bunch of nodes which are connected by arrows pointing from cause to consequence.
Elementary example with 2 nodes: Cause -> Consequence.
How CCN looks like with all known about
the issue plus some speculated/hypothesised/unpublished/non-peer-reviewed stuff included.
What are initial/the_top causes ?
What are end/final/the_bottom consequences ?
What loops are there ? etc...
Source:
Quantum Network Theory (Part 1)