I'm reminded of Maslowski's list of climatic processes that are omitted from, or poorly represented in, most current-generation models (due to constraints such as the availability of data, the existence of algorithms, computational cost, our knowledge of physics, the amount of time scientists have, and the limitations of computability):
"Oceanic eddies, tides, fronts, buoyancy-driven coastal and boundary currents, cold halocline, dense water plumes and convection, double diffusion, surface/bottom mixed layer, sea ice–thickness distribution, concentration, deformation, drift and export, fast ice, snow cover, melt ponds and surface albedo, atmospheric loading, clouds and fronts, ice sheets/caps and mountain glaciers, permafrost, river runoff, and air–sea ice–land interactions and coupling."
That's a lot of 'unknowns' to potentially combine under a regime of substantially increased temperatures to produce a substantially different outcome.