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Author Topic: Meta-human  (Read 5571 times)

ivica

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Meta-human
« on: September 20, 2013, 01:24:43 PM »
Let me define meta-human as a human aware of metagenome and its meaning.

It is fresh new breakthrough of natural science:

Dusko Ehrlich - INRA & MetaHIT coordinator


Notes from Café:
   Introduction
   Dr. Ehrlich's dream, Personalized Medicine
   Effect on BAU
   Metagenomic's breakthrough 
   Video, understand the importance of gut microbiota

Links:
   Gut Microbiota World Watch
   Online information centre to expand knowledge about the topic and its importance for health and quality of life among the media and society in general.

---
More to follow, work in progress...

In short:
   I'm as earthling composition of 150+ species, my own well being strongly depends on them.
Thinking progressively, how can I enhance cooperation with them, hmm...
Meanwhile, wherever I go I'm not alone. :)

« Last Edit: September 20, 2013, 01:46:31 PM by ivica »

ivica

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Re: Meta-human
« Reply #1 on: September 21, 2013, 10:57:14 AM »
The most exciting for me is that our new insight - that we are assembly of different species - fits nicely to the progressive trend of Nature: ...->atoms->molecules->life->...

Which person is more likely to be environment (Earth+) friendly,
meta-human or one which denies natural science ?



ivica

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Re: Meta-human
« Reply #2 on: September 22, 2013, 10:41:20 AM »
Microbiota which lives on and in us constitues ecosystem, every human have one (called enterotype).
Be sure that your ecosystem is in good condition or you could find yourself in serious trouble, you do not want mess with 100 trillion microbes.

That should be communicated to people, that they have their own ecosystem and that their well being directly depends on that. Resulted awarenes could change how they treat outer ecosystem.

Nice sentence at the end of speech here ends saying: “We are them. They are us”.

We're Mainly Microbe, so, stay away from antibiotics as much as possible, think about probiotics and prebiotics.

---
"Evolution is cleverer than you are" Orgel's rule.


ivica

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Re: Meta-human
« Reply #3 on: September 22, 2013, 07:16:36 PM »
Note on terminology:
Technical term more in use in EU is "microbiota", "microbiom" in USA.
All microorganisms that reside either on the surface or in deep layers of skin, in the oral mucosa and saliva, in the conjunctiva, in the gastrointestinal tract and other parts of the body.

"Microbes", "bacteria", "flora" are PR terms to make communication simpler. Better explanation is here.

Note on numbers:
We are 99% bacterial: 100 times more bacterial genes than human genes.
30% of nutrients from food we eat is processed by gut microbiota, at 4:45 here.

BTW: “How bacteria talk”.

ivica

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Re: Meta-human
« Reply #4 on: August 15, 2015, 01:25:03 AM »
Discovered in 1982, Helicobacter pylori (H. pylori) is a disease-causing bacterium that survives in our stomachs despite the harsh acidic conditions. It is estimated that one in two people have got it, though most won't ever experience any problems. Even so, it is considered one of the most common bacterial infections worldwide and a leading cause of dyspepsia, peptic ulceration and gastric cancer.

Read more at: http://phys.org/news/2015-08-revealed-helicobacter-pylori-secret-weapon.html#jCp

ivica

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Re: Meta-human
« Reply #5 on: August 22, 2015, 11:32:51 AM »
Inspired :) by Timothy Chase's comment about chloroplast (August 22, 2015) at robertscribbler blog:

For those who are interested, actually the chloroplasts found in plants that are responsible for plant photosynthesis are endosymbiotic in origin...
“Dating the cyanobacterial ancestor of the chloroplast.” ...

That reminds me on mitochondria.
Symbiogenesis
According to this theory, mitochondria, plastids (for example chloroplasts), and possibly other organelles representing formerly free-living bacteria were taken inside another cell as an endosymbiont around 1.5 billion years ago.


BTW, a few articles at phys.org:

Microbial companions of humans and animals are highly specialized, August 13, 2015:
Humans and animals are never alone. Everyone is host to over two thousand different species of microbes, of which most colonize our bodies only after we are born. One would assume that the generalists among them have an advantage. Zoologists from the Department of Environmental Sciences at the University of Basel have now shown that the opposite is the case. Microbial communities living on humans and animals are mostly dominated by specialists.

Classifying microbial species in the genomics era, July 27, 2015:
The rapid explosion in the throughput of DNA sequencing due to new technology platforms is fueling an increase in the number of sequenced microbial genomes and driving much greater availability of these data to the research community.

Newfound groups of bacteria are mixing up the tree of life, June 15, 2015:
The new groups make up more than 15 percent of all known groups or phyla of bacteria, the scientists say, and include the smallest life forms on Earth, microbes a mere 400 nanometers across. The number of new bacterial phyla is equal to all the known animal phyla on Earth.

First detailed microscopy evidence of bacteria at the lower size limit of life, February 27, 2015:
About 150 of these bacteria could fit inside an Escherichia coli cell and more than 150,000 cells could fit onto the tip of a human hair.


ivica

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Re: Meta-human
« Reply #6 on: January 12, 2017, 02:16:43 PM »
A-Team: There's not a lot of energy to be gleaned in an autotrophic environment using molecular hydrogen as terminal oxidant with a nickel cofactor catalyst poisoned by early oxygen, but a big breakthrough from the anthropomorphic perspective came from a cooperative symbiosis with a micro-aerobic planktonic marine ?-proteobacteria, later to become a  talent-sharing endosymbiont known as the mitochondrion.

Mitochondria: common factors for eukaryotes and not too far from 'others'. They are *everywhere*, and so many variations, how do they communicate with environment, with others? little fellows, sooo complex..
Thank you for putting them back into my head. I need them :)   

Some notes & videos:
---------------------------

"The Excitable Mitochondria" by John Hewitt.
"On the fundamental units of the nervous system."
I shall argue that the fundamental, discrete units of the nervous system are its mitochondria. The feature that we expect of an irreducible neural component is excitability. Mitochondria take excitability to an extreme. If mitochondria are the fundamental units of the nervous systems, then in any CAD model of the brain, they are precisely the parts to which the most care and attention should be applied.


"Tiny Conspiracies: Cell-to-Cell Communication in Bacteria," by Bonnie Bassler
Intra/inter-species communication, tribalism/social behaviour of bacterial life, uf. New potential drugs, saturating sensors by dummy signal should make them "unaware but compliant". Some do that to humans so why not to bacteria, what possibly could go wrong?

Bonnie Bassler: "The Secret, Social Lives of Bacteria" | Spring 2015 Wall Exchange
P. Greenberg - Quorum sensing and cooperation in bacteria..

--

"Super-Saturated Chemistry" by Marc Henry.
"On the relationship between physics and chemistry."

"Chiral Induced Spin Selectivity" reviewed by James Tour.

-

all there should be a lot of 'emergent properties' which distinguish one from a mere walking bag of mitochondria.         
gone to count some beans er permutations.


magnamentis

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Re: Meta-human
« Reply #7 on: January 13, 2017, 06:55:46 PM »
A-Team: There's not a lot of energy to be gleaned in an autotrophic environment using molecular hydrogen as terminal oxidant with a nickel cofactor catalyst poisoned by early oxygen, but a big breakthrough from the anthropomorphic perspective came from a cooperative symbiosis with a micro-aerobic planktonic marine ?-proteobacteria, later to become a  talent-sharing endosymbiont known as the mitochondrion.

Mitochondria: common factors for eukaryotes and not too far from 'others'. They are *everywhere*, and so many variations, how do they communicate with environment, with others? little fellows, sooo complex..
Thank you for putting them back into my head. I need them :)   

Some notes & videos:
---------------------------

"The Excitable Mitochondria" by John Hewitt.
"On the fundamental units of the nervous system."
I shall argue that the fundamental, discrete units of the nervous system are its mitochondria. The feature that we expect of an irreducible neural component is excitability. Mitochondria take excitability to an extreme. If mitochondria are the fundamental units of the nervous systems, then in any CAD model of the brain, they are precisely the parts to which the most care and attention should be applied.


"Tiny Conspiracies: Cell-to-Cell Communication in Bacteria," by Bonnie Bassler
Intra/inter-species communication, tribalism/social behaviour of bacterial life, uf. New potential drugs, saturating sensors by dummy signal should make them "unaware but compliant". Some do that to humans so why not to bacteria, what possibly could go wrong?

Bonnie Bassler: "The Secret, Social Lives of Bacteria" | Spring 2015 Wall Exchange
P. Greenberg - Quorum sensing and cooperation in bacteria..

--

"Super-Saturated Chemistry" by Marc Henry.
"On the relationship between physics and chemistry."

"Chiral Induced Spin Selectivity" reviewed by James Tour.

-

all there should be a lot of 'emergent properties' which distinguish one from a mere walking bag of mitochondria.         
gone to count some beans er permutations.


since there is no button for appreciation still i just want to give kudos for the repeatingly good reads and stuff you're providing over quite some time. thanks

lijepa večer i ugodan vikend
http://magnamentis.com
Knowledge, Understanding & Insight Are Among The Best Sources For Personal Freedom & Vitality !

ivica

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Re: Meta-human
« Reply #8 on: January 27, 2017, 01:22:08 PM »
magnamentis, thanks for your kind words!
coming soon...
« Last Edit: January 27, 2017, 01:27:43 PM by ivica »